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Original Research Article

Phytochemical Analysis and Antifungal Activity of Vitex negundo Leaf Extracts Against Clinically Isolated Fungal Pathogens

Anbalagan S, Sankareswaran M* , Moorthy M, Elakkia B and Fahamitha E.

Department of Microbiology, Muthayammal College of Arts and Science, Rasipuram.

Ind.J.Applied.Microbiol. 2017 .20(2) : 119-125

*Corresponding author


The aim of this study is to examine the antifungal activity of plant Vitex negundo Linn. Disc diffusion method was used to assess the antifungal activity of these extracts against clinically isolated fungal pathogens, such as Candida albicans, Aspergillus niger, Mucor sp, Cryptococcus neoformans, Penicillium sp. The presence of phyto-compound in the extracts including, steroid, terpenoids, flavonoids, may be responsible for these activities. In ethanol extract of Vitex negundo showed the highest inhibition zone against Candida albicans and the growth of Penicillium sp were inhibited by methanol extract. The results clearly showed that ethanol and methanol extracts were specific in action against the fungal pathogens.

Keywords: Vitex negundo, fungal strains, Phytochemical analysis, antifungal activity

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